CYP450 154229-19-3 C24H31NO Abiraterone

Abiraterone CAS No.154229-19-3

Product Name: Abiraterone
Full English name:ABT 17-(3-pyridyl)androsta-5,16-dien-3β-ol abiraterone
CAS No:154229-19-3
Molecular formula : C24H31NO
Molecular weight : 349.51
Physical and chemical properties
Melting point 227-228 ° C; density 1.14 ± 0.1 g / cm3
Abiterone is an oral cytochrome oxidase P450 (CYP450) C17 inhibitor. It can reduce the androgen level by inhibiting CYP450 C17, the key enzyme in androgen synthesis, and it can inhibit the androgen in testis and other parts of the body. Androgen antagonist is a prostate cancer treatment drug. Its English name is abiraterone. It has not been sold in China. It was invented by researchers at Royal Marsden Hospital (the world famous cancer research and treatment center) in southwest London. Chemical book can inhibit androgen production in any part of the body. It can not only reduce the level of prostate specific antigen (PSA), which represents tumor activity, but also help to reduce tumor. At the same time, it can be applied to cancer patients who have received chemotherapy in the past, showing the hope of treatment.